You can pick up your rental car in the United States at the airport or after your visit to New York City. In the city itself, you are better off using the inexpensive subway and bus facilities. Within New York City/Manhattan, there are several locations where car rentals are available. Car rental is relatively inexpensive in the United States. Check the website for the attractive rates. From here you can travel south, for example via Washington DC, Atlanta or to Florida. We suggest you visit the Kennedy Space Center, while you still can, for a stunning overview of the United Statesn space history. Return the car to any international airport of your choice. With Avis, this is an option at almost every airport in the United States.